BRD-K47639036_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K47639036_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
APOD apolipoprotein D
BMP2 bone morphogenetic protein 2
CXCL13 chemokine (C-X-C motif) ligand 13
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EZR ezrin
FBN2 fibrillin 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFITM1 interferon induced transmembrane protein 1
IL1RN interleukin 1 receptor antagonist
IL32 interleukin 32
KRT17 keratin 17, type I
KRT7 keratin 7, type II
MYBPC1 myosin binding protein C, slow type
NEB nebulin
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PPL periplakin
PTN pleiotrophin
RSAD2 radical S-adenosyl methionine domain containing 2
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
VEGFA vascular endothelial growth factor A
VSNL1 visinin-like 1
XAF1 XIAP associated factor 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
CCNH cyclin H
EPCAM epithelial cell adhesion molecule
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ITM2C integral membrane protein 2C
MBNL1 muscleblind-like splicing regulator 1
MMD monocyte to macrophage differentiation-associated
MPO myeloperoxidase
NPY1R neuropeptide Y receptor Y1
RIPK2 receptor-interacting serine-threonine kinase 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
WWP1 WW domain containing E3 ubiquitin protein ligase 1