BRD-K47598052_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

110 genes differentially expressed following the BRD-K47598052_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACADVL acyl-CoA dehydrogenase, very long chain
APOD apolipoprotein D
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
ARHGAP29 Rho GTPase activating protein 29
ASPN asporin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX4 brain expressed, X-linked 4
CA2 carbonic anhydrase II
CD24 CD24 molecule
CD9 CD9 molecule
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CHGB chromogranin B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL1A1 collagen, type I, alpha 1
COL8A2 collagen, type VIII, alpha 2
CPE carboxypeptidase E
CRABP1 cellular retinoic acid binding protein 1
CRABP2 cellular retinoic acid binding protein 2
CTGF connective tissue growth factor
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DACH1 dachshund family transcription factor 1
DARS aspartyl-tRNA synthetase
DDR1 discoidin domain receptor tyrosine kinase 1
DLK1 delta-like 1 homolog (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL2 dihydropyrimidinase-like 2
DUSP4 dual specificity phosphatase 4
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
FGFR2 fibroblast growth factor receptor 2
FN1 fibronectin 1
FRZB frizzled-related protein
GAS1 growth arrest-specific 1
GREM1 gremlin 1, DAN family BMP antagonist
GSN gelsolin
HIST1H1C histone cluster 1, H1c
HIST2H2BE histone cluster 2, H2be
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
IRS2 insulin receptor substrate 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
LDLR low density lipoprotein receptor
LXN latexin
MACF1 microtubule-actin crosslinking factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAST4 microtubule associated serine/threonine kinase family member 4
MED13L mediator complex subunit 13-like
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NPTX2 neuronal pentraxin II
OBSL1 obscurin-like 1
OLFML3 olfactomedin-like 3
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PDE4DIP phosphodiesterase 4D interacting protein
PDZK1 PDZ domain containing 1
PDZK1IP1 PDZK1 interacting protein 1
PEG3 paternally expressed 3
PON3 paraoxonase 3
PRUNE2 prune homolog 2 (Drosophila)
RAB13 RAB13, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
REEP1 receptor accessory protein 1
RGS5 regulator of G-protein signaling 5
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RTN2 reticulon 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC35E2B solute carrier family 35, member E2B
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SYT1 synaptotagmin I
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THBS1 thrombospondin 1
THBS2 thrombospondin 2
WT1 Wilms tumor 1
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
ANPEP alanyl (membrane) aminopeptidase
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
CCDC85B coiled-coil domain containing 85B
CCDC86 coiled-coil domain containing 86
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCND1 cyclin D1
CTSC cathepsin C
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM129A family with sequence similarity 129, member A
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRWD1 glutamate-rich WD repeat containing 1
HOMER2 homer scaffolding protein 2
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRF4 interferon regulatory factor 4
MUC4 mucin 4, cell surface associated
NQO1 NAD(P)H dehydrogenase, quinone 1
ODC1 ornithine decarboxylase 1
PITRM1 pitrilysin metallopeptidase 1
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PRMT1 protein arginine methyltransferase 1