BRD-K47598052_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

71 genes differentially expressed following the BRD-K47598052_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCNG2 cyclin G2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
EFNA1 ephrin-A1
EGFL6 EGF-like-domain, multiple 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ERBB3 erb-b2 receptor tyrosine kinase 3
HBP1 HMG-box transcription factor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
KLHDC2 kelch domain containing 2
MAGED1 melanoma antigen family D1
MAGED2 melanoma antigen family D2
MAOA monoamine oxidase A
NRIP1 nuclear receptor interacting protein 1
RBM47 RNA binding motif protein 47
RPS4Y1 ribosomal protein S4, Y-linked 1
SFRP4 secreted frizzled-related protein 4
SLC35E2B solute carrier family 35, member E2B
SOX4 SRY (sex determining region Y)-box 4
SSPN sarcospan
TSC22D3 TSC22 domain family, member 3
WBP1L WW domain binding protein 1-like
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
AREG amphiregulin
CDC25A cell division cycle 25A
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CTPS1 CTP synthase 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPH2 DPH2 homolog (S. cerevisiae)
DUSP14 dual specificity phosphatase 14
EIF4E eukaryotic translation initiation factor 4E
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GEM GTP binding protein overexpressed in skeletal muscle
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBEGF heparin-binding EGF-like growth factor
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INPP1 inositol polyphosphate-1-phosphatase
JMJD6 jumonji domain containing 6
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LDLR low density lipoprotein receptor
MCL1 myeloid cell leukemia 1
MSMO1 methylsterol monooxygenase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOP16 NOP16 nucleolar protein
NOP2 NOP2 nucleolar protein
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PEA15 phosphoprotein enriched in astrocytes 15
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PNP purine nucleoside phosphorylase
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTRH2 peptidyl-tRNA hydrolase 2
RGS2 regulator of G-protein signaling 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
STK17A serine/threonine kinase 17a
STOM stomatin
TFF3 trefoil factor 3 (intestinal)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPM4 tropomyosin 4
TSC22D2 TSC22 domain family, member 2
TUBB2A tubulin, beta 2A class IIa