BRD-K46692335_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K46692335_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGR2 anterior gradient 2
BASP1 brain abundant, membrane attached signal protein 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1R1 interleukin 1 receptor, type I
INSIG1 insulin induced gene 1
PIR pirin (iron-binding nuclear protein)
PLAU plasminogen activator, urokinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SRPX sushi-repeat containing protein, X-linked
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
XBP1 X-box binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
CLEC2B C-type lectin domain family 2, member B
EDN1 endothelin 1
FRZB frizzled-related protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP7 insulin-like growth factor binding protein 7
NAP1L1 nucleosome assembly protein 1-like 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
ZEB1 zinc finger E-box binding homeobox 1