BRD-K46692335_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K46692335_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL5 acyl-CoA synthetase long-chain family member 5
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AQP3 aquaporin 3 (Gill blood group)
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLIC3 chloride intracellular channel 3
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL3A1 collagen, type III, alpha 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CXCL9 chemokine (C-X-C motif) ligand 9
DMD dystrophin
EGFR epidermal growth factor receptor
EIF5 eukaryotic translation initiation factor 5
FABP4 fatty acid binding protein 4, adipocyte
FLRT2 fibronectin leucine rich transmembrane protein 2
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GLUL glutamate-ammonia ligase
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
INSIG1 insulin induced gene 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LRP4 low density lipoprotein receptor-related protein 4
MSX1 msh homeobox 1
MTA1 metastasis associated 1
MTSS1 metastasis suppressor 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLA2G16 phospholipase A2, group XVI
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RELN reelin
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC38A2 solute carrier family 38, member 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLR4 toll-like receptor 4
TRAT1 T cell receptor associated transmembrane adaptor 1
VCAN versican
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AREG amphiregulin
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATM ATM serine/threonine kinase
BAX BCL2-associated X protein
BLNK B-cell linker
CD9 CD9 molecule
EPN2 epsin 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGSF3 immunoglobulin superfamily, member 3
LAPTM5 lysosomal protein transmembrane 5
MEIS2 Meis homeobox 2
MXRA7 matrix-remodelling associated 7
NBL1 neuroblastoma 1, DAN family BMP antagonist
NPY neuropeptide Y
PALLD palladin, cytoskeletal associated protein
SOCS2 suppressor of cytokine signaling 2
TCF21 transcription factor 21
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
ZNF652 zinc finger protein 652