BRD-K46558254_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-K46558254_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CTSE cathepsin E
DACH1 dachshund family transcription factor 1
DDIT4 DNA-damage-inducible transcript 4
DEFA5 defensin, alpha 5, Paneth cell-specific
ERBB2 erb-b2 receptor tyrosine kinase 2
FGFR2 fibroblast growth factor receptor 2
GPM6A glycoprotein M6A
GRN granulin
HEPH hephaestin
LOC100505650 uncharacterized LOC100505650
LRMP lymphoid-restricted membrane protein
MAP3K5 mitogen-activated protein kinase kinase kinase 5
PLXNB2 plexin B2
PRUNE2 prune homolog 2 (Drosophila)
PSAP prosaposin
QPCT glutaminyl-peptide cyclotransferase
RAP1GAP RAP1 GTPase activating protein
SPINK4 serine peptidase inhibitor, Kazal type 4
TBX3 T-box 3
TGFA transforming growth factor, alpha
TGFBI transforming growth factor, beta-induced, 68kDa
TIPARP TCDD-inducible poly(ADP-ribose) polymerase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
AK4 adenylate kinase 4
BIRC5 baculoviral IAP repeat containing 5
CCNB2 cyclin B2
CDC20 cell division cycle 20
CDKN3 cyclin-dependent kinase inhibitor 3
CSRP2 cysteine and glycine-rich protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
G0S2 G0/G1 switch 2
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HSPA13 heat shock protein 70kDa family, member 13
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
KRT17 keratin 17, type I
LTF lactotransferrin
LUM lumican
PBK PDZ binding kinase
PCNA proliferating cell nuclear antigen
SAR1B secretion associated, Ras related GTPase 1B
TMSB15A thymosin beta 15a
TOP2A topoisomerase (DNA) II alpha 170kDa