BRD-K46441700_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K46441700_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHCR7 7-dehydrocholesterol reductase
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP4 fatty acid binding protein 4, adipocyte
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP4 insulin-like growth factor binding protein 4
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PCP4 Purkinje cell protein 4
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A10 S100 calcium binding protein A10
SC5D sterol-C5-desaturase
SGK1 serum/glucocorticoid regulated kinase 1
SQLE squalene epoxidase

decreased expression

Symbol Name
COL6A1 collagen, type VI, alpha 1
DSP desmoplakin
HEPH hephaestin
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA8 heat shock 70kDa protein 8
JCHAIN joining chain of multimeric IgA and IgM
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
VEGFA vascular endothelial growth factor A