BRD-K46373671_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K46373671_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
ADGRF5 adhesion G protein-coupled receptor F5
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AHR aryl hydrocarbon receptor
ARF4 ADP-ribosylation factor 4
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
C1ORF54 chromosome 1 open reading frame 54
C6ORF62 chromosome 6 open reading frame 62
CALR calreticulin
CD59 CD59 molecule, complement regulatory protein
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEMIP cell migration inducing protein, hyaluronan binding
CFI complement factor I
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL3A1 collagen, type III, alpha 1
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DCN decorin
EDNRB endothelin receptor type B
EXOSC4 exosome component 4
FAP fibroblast activation protein, alpha
FRZB frizzled-related protein
GDF15 growth differentiation factor 15
GPR137B G protein-coupled receptor 137B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IER3 immediate early response 3
LMO2 LIM domain only 2 (rhombotin-like 1)
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC17 leucine rich repeat containing 17
LTBP1 latent transforming growth factor beta binding protein 1
LUM lumican
LXN latexin
MAN1A1 mannosidase, alpha, class 1A, member 1
METTL7A methyltransferase like 7A
MGP matrix Gla protein
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MTA1 metastasis associated 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYO1B myosin IB
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PDGFC platelet derived growth factor C
PFN2 profilin 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAT plasminogen activator, tissue
RAB29 RAB29, member RAS oncogene family
RGS5 regulator of G-protein signaling 5
RHOBTB3 Rho-related BTB domain containing 3
RNF167 ring finger protein 167
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRY2 sprouty homolog 2 (Drosophila)
SRGN serglycin
STOM stomatin
STX1A syntaxin 1A (brain)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX2 T-box 2
THBS2 thrombospondin 2
TSPAN13 tetraspanin 13
TXNDC9 thioredoxin domain containing 9
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ALOX15B arachidonate 15-lipoxygenase, type B
CKB creatine kinase, brain
CLDN1 claudin 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
ERBB2 erb-b2 receptor tyrosine kinase 2
GAL galanin/GMAP prepropeptide
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
IRS2 insulin receptor substrate 2
LDOC1 leucine zipper, down-regulated in cancer 1
MCOLN1 mucolipin 1
MICALL1 MICAL-like 1
MX1 MX dynamin-like GTPase 1
SCGB2A2 secretoglobin, family 2A, member 2
TLE4 transducin-like enhancer of split 4
XIST X inactive specific transcript (non-protein coding)