BRD-K46373671_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K46373671_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL2A1 BCL2-related protein A1
CD200 CD200 molecule
CD52 CD52 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CPA3 carboxypeptidase A3 (mast cell)
CRABP2 cellular retinoic acid binding protein 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DENND2D DENN/MADD domain containing 2D
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DRAM1 DNA-damage regulated autophagy modulator 1
EIF5A eukaryotic translation initiation factor 5A
FHL1 four and a half LIM domains 1
FNBP1L formin binding protein 1-like
GPR137B G protein-coupled receptor 137B
GSN gelsolin
HBB hemoglobin, beta
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
ISG20 interferon stimulated exonuclease gene 20kDa
KLF2 Kruppel-like factor 2
KRT18 keratin 18, type I
LIMCH1 LIM and calponin homology domains 1
LXN latexin
MARCKSL1 MARCKS-like 1
MCAM melanoma cell adhesion molecule
MEST mesoderm specific transcript
NEBL nebulette
PLAT plasminogen activator, tissue
RHOB ras homolog family member B
S100A4 S100 calcium binding protein A4
SLC16A4 solute carrier family 16, member 4
SLC16A6 solute carrier family 16, member 6
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SMAD3 SMAD family member 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRGN serglycin
TCTA T-cell leukemia translocation altered
TNIK TRAF2 and NCK interacting kinase
TPD52L1 tumor protein D52-like 1
TPM2 tropomyosin 2 (beta)

decreased expression

Symbol Name
ASS1 argininosuccinate synthase 1
C1S complement component 1, s subcomponent
CCND1 cyclin D1
CNPY3 canopy FGF signaling regulator 3
COL5A2 collagen, type V, alpha 2
CTSG cathepsin G
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
LAPTM4B lysosomal protein transmembrane 4 beta
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PLTP phospholipid transfer protein
PPL periplakin
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SPRR1B small proline-rich protein 1B