BRD-K46137903_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K46137903_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASPH aspartate beta-hydroxylase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C2CD2 C2 calcium-dependent domain containing 2
CA2 carbonic anhydrase II
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
EMP1 epithelial membrane protein 1
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LYZ lysozyme
NT5E 5'-nucleotidase, ecto (CD73)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSPAN7 tetraspanin 7

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
BACE2 beta-site APP-cleaving enzyme 2
DAPK1 death-associated protein kinase 1
DPYSL2 dihydropyrimidinase-like 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM46A family with sequence similarity 46, member A
FLRT3 fibronectin leucine rich transmembrane protein 3
IFI27 interferon, alpha-inducible protein 27
IGF1R insulin-like growth factor 1 receptor
IL1B interleukin 1, beta
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MARCKS myristoylated alanine-rich protein kinase C substrate
MYL9 myosin, light chain 9, regulatory
PEG10 paternally expressed 10
PRDX4 peroxiredoxin 4
SNX7 sorting nexin 7
TSPAN13 tetraspanin 13
ZFPM2 zinc finger protein, FOG family member 2