BRD-K46056750_AZD-7762_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

66 genes differentially expressed following the BRD-K46056750_AZD-7762_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOD apolipoprotein D
AURKA aurora kinase A
CCL20 chemokine (C-C motif) ligand 20
CDC20 cell division cycle 20
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
DLK1 delta-like 1 homolog (Drosophila)
FABP7 fatty acid binding protein 7, brain
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGF13 fibroblast growth factor 13
GAS1 growth arrest-specific 1
GREB1 growth regulation by estrogen in breast cancer 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LDLR low density lipoprotein receptor
MFAP5 microfibrillar associated protein 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PDGFC platelet derived growth factor C
RAB21 RAB21, member RAS oncogene family
S100P S100 calcium binding protein P
SCO2 SCO2 cytochrome c oxidase assembly protein
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TES testin LIM domain protein
TUBB2A tubulin, beta 2A class IIa
WDR7 WD repeat domain 7
XIST X inactive specific transcript (non-protein coding)
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AEBP1 AE binding protein 1
AKAP12 A kinase (PRKA) anchor protein 12
CADM1 cell adhesion molecule 1
CD200 CD200 molecule
CHGB chromogranin B
CHN1 chimerin 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENO2 enolase 2 (gamma, neuronal)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA8 heat shock 70kDa protein 8
JADE2 jade family PHD finger 2
JCHAIN joining chain of multimeric IgA and IgM
LCN2 lipocalin 2
LIMCH1 LIM and calponin homology domains 1
LOX lysyl oxidase
MECOM MDS1 and EVI1 complex locus
MFAP4 microfibrillar-associated protein 4
OAT ornithine aminotransferase
PDE10A phosphodiesterase 10A
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RPS11 ribosomal protein S11
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SNAP25 synaptosomal-associated protein, 25kDa
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TRIM2 tripartite motif containing 2
VTCN1 V-set domain containing T cell activation inhibitor 1