BRD-K46056750_AZD-7762_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K46056750_AZD-7762_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AURKA aurora kinase A
CCL19 chemokine (C-C motif) ligand 19
CFH complement factor H
CHN1 chimerin 1
CSRP2 cysteine and glycine-rich protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
CYR61 cysteine-rich, angiogenic inducer, 61
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FABP7 fatty acid binding protein 7, brain
FAM46A family with sequence similarity 46, member A
FBP1 fructose-1,6-bisphosphatase 1
FGF13 fibroblast growth factor 13
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GRB14 growth factor receptor-bound protein 14
GREM1 gremlin 1, DAN family BMP antagonist
HDAC6 histone deacetylase 6
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPB8 heat shock 22kDa protein 8
KLF10 Kruppel-like factor 10
LAMP5 lysosomal-associated membrane protein family, member 5
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MFAP3L microfibrillar-associated protein 3-like
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PDGFC platelet derived growth factor C
PDZK1 PDZ domain containing 1
PON3 paraoxonase 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
RCAN1 regulator of calcineurin 1
RPS27L ribosomal protein S27-like
SDC2 syndecan 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
STK26 serine/threonine protein kinase 26
TAGLN transgelin
TES testin LIM domain protein
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD14 CD14 molecule
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CX3CR1 chemokine (C-X3-C motif) receptor 1
FAS Fas cell surface death receptor
FCGBP Fc fragment of IgG binding protein
GBP2 guanylate binding protein 2, interferon-inducible
HBB hemoglobin, beta
IFI16 interferon, gamma-inducible protein 16
IFITM3 interferon induced transmembrane protein 3
IGL immunoglobulin lambda locus
ISYNA1 inositol-3-phosphate synthase 1
KCTD12 potassium channel tetramerization domain containing 12
KLK10 kallikrein-related peptidase 10
MTERF3 mitochondrial transcription termination factor 3
NID2 nidogen 2 (osteonidogen)
NT5DC2 5'-nucleotidase domain containing 2
OLFM4 olfactomedin 4
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A9 S100 calcium binding protein A9
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLPI secretory leukocyte peptidase inhibitor
VSIG4 V-set and immunoglobulin domain containing 4
VTCN1 V-set domain containing T cell activation inhibitor 1