BRD-K46056750_AZD-7762_LNCAP_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

74 genes differentially expressed following the BRD-K46056750_AZD-7762_LNCAP_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ARG2 arginase 2
AURKA aurora kinase A
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CA12 carbonic anhydrase XII
CDC20 cell division cycle 20
CDC42 cell division cycle 42
CEMIP cell migration inducing protein, hyaluronan binding
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CSRP2 cysteine and glycine-rich protein 2
CSTA cystatin A (stefin A)
CTH cystathionine gamma-lyase
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DUSP1 dual specificity phosphatase 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBN1 fibrillin 1
GAS1 growth arrest-specific 1
HOXB6 homeobox B6
HOXB7 homeobox B7
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP6 insulin-like growth factor binding protein 6
IGHD immunoglobulin heavy constant delta
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KRT13 keratin 13, type I
KRT15 keratin 15, type I
LIMA1 LIM domain and actin binding 1
LXN latexin
MAN1A1 mannosidase, alpha, class 1A, member 1
NELL2 NEL-like 2 (chicken)
NOSIP nitric oxide synthase interacting protein
PCNA proliferating cell nuclear antigen
PSRC1 proline/serine-rich coiled-coil 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA5 annexin A5
ATP9A ATPase, class II, type 9A
CTSB cathepsin B
DIO2 deiodinase, iodothyronine, type II
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
HIRA histone cell cycle regulator
IFI27 interferon, alpha-inducible protein 27
IGFBP7 insulin-like growth factor binding protein 7
LGALS3 lectin, galactoside-binding, soluble, 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LIMCH1 LIM and calponin homology domains 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LYZ lysozyme
MEF2C myocyte enhancer factor 2C
MT1E metallothionein 1E
PROM1 prominin 1
PRSS3 protease, serine, 3
RUNX1 runt-related transcription factor 1
SATB1 SATB homeobox 1
SEC63 SEC63 homolog (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SESN1 sestrin 1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SOX9 SRY (sex determining region Y)-box 9
TBX3 T-box 3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TMSB15A thymosin beta 15a
TNPO1 transportin 1
TSPAN8 tetraspanin 8