BRD-K46056750_AZD-7762_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K46056750_AZD-7762_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCND2 cyclin D2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPHA3 EPH receptor A3
IGHM immunoglobulin heavy constant mu
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
ITM2A integral membrane protein 2A
KDM5D lysine (K)-specific demethylase 5D
KIF5C kinesin family member 5C
LCN2 lipocalin 2
LTBP2 latent transforming growth factor beta binding protein 2
LUM lumican
MOXD1 monooxygenase, DBH-like 1
MYB v-myb avian myeloblastosis viral oncogene homolog
PTCH1 patched 1
SAP30 Sin3A-associated protein, 30kDa
SIK1 salt-inducible kinase 1
SOCS2 suppressor of cytokine signaling 2
TRIM2 tripartite motif containing 2
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
ARHGAP29 Rho GTPase activating protein 29
CA2 carbonic anhydrase II
CD200 CD200 molecule
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CYR61 cysteine-rich, angiogenic inducer, 61
DCK deoxycytidine kinase
DLD dihydrolipoamide dehydrogenase
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOSL1 FOS-like antigen 1
FST follistatin
GADD45A growth arrest and DNA-damage-inducible, alpha
GJA1 gap junction protein, alpha 1, 43kDa
H1F0 H1 histone family, member 0
HHEX hematopoietically expressed homeobox
HSPA1A heat shock 70kDa protein 1A
IER3 immediate early response 3
IGFBP5 insulin-like growth factor binding protein 5
ISG15 ISG15 ubiquitin-like modifier
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MX1 MX dynamin-like GTPase 1
MYBPC1 myosin binding protein C, slow type
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK2 polo-like kinase 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RPF1 ribosome production factor 1 homolog (S. cerevisiae)
SAMD4A sterile alpha motif domain containing 4A
SCG2 secretogranin II
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
THBS1 thrombospondin 1
VCAN versican
XIST X inactive specific transcript (non-protein coding)