BRD-K45542213_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K45542213_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
ATP11B ATPase, class VI, type 11B
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CCR2 chemokine (C-C motif) receptor 2
CD200 CD200 molecule
CD44 CD44 molecule (Indian blood group)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
DACH1 dachshund family transcription factor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYD dihydropyrimidine dehydrogenase
DST dystonin
DUSP5 dual specificity phosphatase 5
EFHD1 EF-hand domain family, member D1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FHL1 four and a half LIM domains 1
GPNMB glycoprotein (transmembrane) nmb
HOPX HOP homeobox
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IGFBP7 insulin-like growth factor binding protein 7
ITGA8 integrin, alpha 8
KLF4 Kruppel-like factor 4 (gut)
KRT15 keratin 15, type I
MDFIC MyoD family inhibitor domain containing
MEF2C myocyte enhancer factor 2C
MTSS1 metastasis suppressor 1
PRNP prion protein
RCAN2 regulator of calcineurin 2
S100A8 S100 calcium binding protein A8
SGK1 serum/glucocorticoid regulated kinase 1
SLAMF7 SLAM family member 7
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SULF1 sulfatase 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
HOXC6 homeobox C6
IGF1R insulin-like growth factor 1 receptor
IGFBP4 insulin-like growth factor binding protein 4
NR2F6 nuclear receptor subfamily 2, group F, member 6
RPS4Y1 ribosomal protein S4, Y-linked 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SOX4 SRY (sex determining region Y)-box 4
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAT1 vesicle amine transport 1