BRD-K45542189_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K45542189_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOD apolipoprotein D
BIK BCL2-interacting killer (apoptosis-inducing)
CCNE2 cyclin E2
COL3A1 collagen, type III, alpha 1
CPVL carboxypeptidase, vitellogenic-like
CRIP1 cysteine-rich protein 1 (intestinal)
CRYAB crystallin, alpha B
DEFB1 defensin, beta 1
EAPP E2F-associated phosphoprotein
FAM107A family with sequence similarity 107, member A
FUCA1 fucosidase, alpha-L- 1, tissue
IL1R2 interleukin 1 receptor, type II
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LTF lactotransferrin
MXRA8 matrix-remodelling associated 8
MYB v-myb avian myeloblastosis viral oncogene homolog
NPC2 Niemann-Pick disease, type C2
PDZK1 PDZ domain containing 1
PER2 period circadian clock 2
PIP prolactin-induced protein
POSTN periostin, osteoblast specific factor
RBP1 retinol binding protein 1, cellular
RCAN1 regulator of calcineurin 1
RRAGD Ras-related GTP binding D
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA10 annexin A10
C6ORF62 chromosome 6 open reading frame 62
CD44 CD44 molecule (Indian blood group)
CLIC4 chloride intracellular channel 4
CPA3 carboxypeptidase A3 (mast cell)
FHL1 four and a half LIM domains 1
GCH1 GTP cyclohydrolase 1
GNAS GNAS complex locus
GRIA2 glutamate receptor, ionotropic, AMPA 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HPCAL1 hippocalcin-like 1
HSPA4 heat shock 70kDa protein 4
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
LIMCH1 LIM and calponin homology domains 1
MAP7 microtubule-associated protein 7
NNMT nicotinamide N-methyltransferase
PAM peptidylglycine alpha-amidating monooxygenase
PRAME preferentially expressed antigen in melanoma
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RGCC regulator of cell cycle
RNF167 ring finger protein 167
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SGK1 serum/glucocorticoid regulated kinase 1
SLC38A2 solute carrier family 38, member 2
SST somatostatin
STX1A syntaxin 1A (brain)
TSPAN12 tetraspanin 12
ZNF586 zinc finger protein 586