BRD-K45399554_CAM-9-027 BRD-K45399554_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-K45399554_CAM-9-027 BRD-K45399554_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACLY ATP citrate lyase
CDK6 cyclin-dependent kinase 6
CSRP1 cysteine and glycine-rich protein 1
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
ELOVL5 ELOVL fatty acid elongase 5
ELOVL6 ELOVL fatty acid elongase 6
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
INSIG1 insulin induced gene 1
MSMB microseminoprotein, beta-
PDGFD platelet derived growth factor D
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEPP1 selenoprotein P, plasma, 1
TOX3 TOX high mobility group box family member 3
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CKS2 CDC28 protein kinase regulatory subunit 2
CRIP2 cysteine-rich protein 2
EXOSC4 exosome component 4
GSTM3 glutathione S-transferase mu 3 (brain)
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
RAD51C RAD51 paralog C
S100A10 S100 calcium binding protein A10