BRD-K45399554_CAM-9-027 BRD-K45399554_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K45399554_CAM-9-027 BRD-K45399554_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BIN1 bridging integrator 1
CD36 CD36 molecule (thrombospondin receptor)
CRYAB crystallin, alpha B
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
FBN2 fibrillin 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
KDM5D lysine (K)-specific demethylase 5D
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOX10 SRY (sex determining region Y)-box 10
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TSPO translocator protein (18kDa)

decreased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASPN asporin
C7 complement component 7
CCNA1 cyclin A1
CD9 CD9 molecule
DENND1B DENN/MADD domain containing 1B
F2RL1 coagulation factor II (thrombin) receptor-like 1
KIAA0922 KIAA0922
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
S100A8 S100 calcium binding protein A8
SMYD2 SET and MYND domain containing 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRED2 sprouty-related, EVH1 domain containing 2
SYT1 synaptotagmin I
TACSTD2 tumor-associated calcium signal transducer 2
TRIB2 tribbles pseudokinase 2
TSPAN7 tetraspanin 7
XIST X inactive specific transcript (non-protein coding)