BRD-K45205755_-666_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K45205755_-666_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BTN3A2 butyrophilin, subfamily 3, member A2
C1S complement component 1, s subcomponent
CBR1 carbonyl reductase 1
CD36 CD36 molecule (thrombospondin receptor)
CXCL13 chemokine (C-X-C motif) ligand 13
FXYD3 FXYD domain containing ion transport regulator 3
GCLC glutamate-cysteine ligase, catalytic subunit
GLI2 GLI family zinc finger 2
GPX2 glutathione peroxidase 2
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGLJ3 immunoglobulin lambda joining 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MFSD10 major facilitator superfamily domain containing 10
NQO1 NAD(P)H dehydrogenase, quinone 1
PDLIM5 PDZ and LIM domain 5
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TALDO1 transaldolase 1
TMEM14A transmembrane protein 14A
TMEM47 transmembrane protein 47
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
AHCY adenosylhomocysteinase
AREG amphiregulin
CHEK1 checkpoint kinase 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KRT5 keratin 5, type II
MPC1 mitochondrial pyruvate carrier 1
MT1G metallothionein 1G
MT1X metallothionein 1X
MYBPC1 myosin binding protein C, slow type
NT5E 5'-nucleotidase, ecto (CD73)
RAI14 retinoic acid induced 14
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFRC transferrin receptor
TNC tenascin C
ZBTB18 zinc finger and BTB domain containing 18