BRD-K45205755_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K45205755_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
BASP1 brain abundant, membrane attached signal protein 1
CAV1 caveolin 1, caveolae protein, 22kDa
CD24 CD24 molecule
CES1 carboxylesterase 1
CKB creatine kinase, brain
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EMP1 epithelial membrane protein 1
ENO2 enolase 2 (gamma, neuronal)
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GLUL glutamate-ammonia ligase
GSTA1 glutathione S-transferase alpha 1
HMOX1 heme oxygenase 1
IGHMBP2 immunoglobulin mu binding protein 2
IGL immunoglobulin lambda locus
KDM5D lysine (K)-specific demethylase 5D
KRT6A keratin 6A, type II
LTF lactotransferrin
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PGD phosphogluconate dehydrogenase
PHACTR2 phosphatase and actin regulator 2
PPAP2B phosphatidic acid phosphatase type 2B
RXRA retinoid X receptor, alpha
SFTPB surfactant protein B
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORBS2 sorbin and SH3 domain containing 2
TPD52L1 tumor protein D52-like 1
TRAC T cell receptor alpha constant
TRBC1 T cell receptor beta constant 1
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ADD3 adducin 3 (gamma)
ADGRG6 adhesion G protein-coupled receptor G6
CALML5 calmodulin-like 5
CAST calpastatin
CCNE2 cyclin E2
COL10A1 collagen, type X, alpha 1
CXCL12 chemokine (C-X-C motif) ligand 12
DENND1B DENN/MADD domain containing 1B
FN1 fibronectin 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
IFI6 interferon, alpha-inducible protein 6
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KRT23 keratin 23, type I
LXN latexin
MGP matrix Gla protein
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
PDGFC platelet derived growth factor C
PLAT plasminogen activator, tissue
PON2 paraoxonase 2
PXDN peroxidasin
RGS5 regulator of G-protein signaling 5
RPS11 ribosomal protein S11
SDC4 syndecan 4
TFPI2 tissue factor pathway inhibitor 2
THBS2 thrombospondin 2