BRD-K45205755_-666_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K45205755_-666_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
BTG1 B-cell translocation gene 1, anti-proliferative
CA12 carbonic anhydrase XII
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSP desmoplakin
EGR1 early growth response 1
EIF1 eukaryotic translation initiation factor 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FNDC3B fibronectin type III domain containing 3B
FOS FBJ murine osteosarcoma viral oncogene homolog
GRB14 growth factor receptor-bound protein 14
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA2 heat shock 70kDa protein 2
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
KDM5D lysine (K)-specific demethylase 5D
KRT14 keratin 14, type I
LTF lactotransferrin
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED1 mediator complex subunit 1
MGP matrix Gla protein
MT1X metallothionein 1X
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX3-1 NK3 homeobox 1
NPC2 Niemann-Pick disease, type C2
PAN2 PAN2 poly(A) specific ribonuclease subunit
RBM47 RNA binding motif protein 47
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A7 S100 calcium binding protein A7
SAT1 spermidine/spermine N1-acetyltransferase 1
SPP1 secreted phosphoprotein 1
STC2 stanniocalcin 2
STXBP1 syntaxin binding protein 1
TXNIP thioredoxin interacting protein
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
APOB apolipoprotein B
APOC3 apolipoprotein C-III
BID BH3 interacting domain death agonist
C1R complement component 1, r subcomponent
CADM1 cell adhesion molecule 1
CALD1 caldesmon 1
CD36 CD36 molecule (thrombospondin receptor)
CPE carboxypeptidase E
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
EMG1 EMG1 N1-specific pseudouridine methyltransferase
FABP4 fatty acid binding protein 4, adipocyte
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FST follistatin
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
MN1 meningioma (disrupted in balanced translocation) 1
PDLIM3 PDZ and LIM domain 3
PEG10 paternally expressed 10
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSCA prostate stem cell antigen
PXDN peroxidasin
RGS1 regulator of G-protein signaling 1
SDC1 syndecan 1
SPON2 spondin 2, extracellular matrix protein
SST somatostatin
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
THBS1 thrombospondin 1
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4