BRD-K44978960_NCGC00010428-03_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K44978960_NCGC00010428-03_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
ANKRD10 ankyrin repeat domain 10
ANKRD36B ankyrin repeat domain 36B
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASNS asparagine synthetase (glutamine-hydrolyzing)
BTG1 B-cell translocation gene 1, anti-proliferative
CA2 carbonic anhydrase II
CXCL12 chemokine (C-X-C motif) ligand 12
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DST dystonin
FABP4 fatty acid binding protein 4, adipocyte
FOXD1 forkhead box D1
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HOXB7 homeobox B7
HOXC6 homeobox C6
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
IRF4 interferon regulatory factor 4
MAN1A1 mannosidase, alpha, class 1A, member 1
MAPT microtubule-associated protein tau
MICALL1 MICAL-like 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
NEFL neurofilament, light polypeptide
NQO1 NAD(P)H dehydrogenase, quinone 1
NT5DC2 5'-nucleotidase domain containing 2
RAD23B RAD23 homolog B (S. cerevisiae)
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TKT transketolase
TXNRD1 thioredoxin reductase 1
VAT1 vesicle amine transport 1
XPO7 exportin 7

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
APOC2 apolipoprotein C-II
ARHGAP29 Rho GTPase activating protein 29
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CFB complement factor B
CFH complement factor H
CKLF chemokine-like factor
CTGF connective tissue growth factor
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP7 fatty acid binding protein 7, brain
FST follistatin
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL1R1 interleukin 1 receptor, type I
LPAR6 lysophosphatidic acid receptor 6
LRRC17 leucine rich repeat containing 17
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MDK midkine (neurite growth-promoting factor 2)
NFIB nuclear factor I/B
NMU neuromedin U
ORM1 orosomucoid 1
PDCD2 programmed cell death 2
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SQLE squalene epoxidase
TACSTD2 tumor-associated calcium signal transducer 2
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TUBA1A tubulin, alpha 1a
VAMP8 vesicle-associated membrane protein 8