BRD-K44510578_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

73 genes differentially expressed following the BRD-K44510578_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADAM28 ADAM metallopeptidase domain 28
AGTR1 angiotensin II receptor, type 1
ALOX5 arachidonate 5-lipoxygenase
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF4 activating transcription factor 4
BLNK B-cell linker
CA2 carbonic anhydrase II
CD99 CD99 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHGB chromogranin B
CLU clusterin
CNPY3 canopy FGF signaling regulator 3
COPS7A COP9 signalosome subunit 7A
CTBP2 C-terminal binding protein 2
CTH cystathionine gamma-lyase
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
MAOB monoamine oxidase B
MAP7 microtubule-associated protein 7
MBNL2 muscleblind-like splicing regulator 2
MYRF myelin regulatory factor
NUCB2 nucleobindin 2
NVL nuclear VCP-like
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G16 phospholipase A2, group XVI
PRAME preferentially expressed antigen in melanoma
S100A8 S100 calcium binding protein A8
SCGB2A1 secretoglobin, family 2A, member 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC38A2 solute carrier family 38, member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SYT1 synaptotagmin I
TGFBI transforming growth factor, beta-induced, 68kDa
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPD52L1 tumor protein D52-like 1
TPSAB1 tryptase alpha/beta 1
TRIM2 tripartite motif containing 2
VEGFA vascular endothelial growth factor A
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
AREG amphiregulin
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
CELF2 CUGBP, Elav-like family member 2
CXCL12 chemokine (C-X-C motif) ligand 12
DHRS2 dehydrogenase/reductase (SDR family) member 2
EFNB2 ephrin-B2
EGR2 early growth response 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOSL1 FOS-like antigen 1
GPNMB glycoprotein (transmembrane) nmb
GRWD1 glutamate-rich WD repeat containing 1
HOMER1 homer scaffolding protein 1
IFI16 interferon, gamma-inducible protein 16
IGL immunoglobulin lambda locus
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LUM lumican
MAGEA3 melanoma antigen family A3
MCL1 myeloid cell leukemia 1
MCUR1 mitochondrial calcium uniporter regulator 1
NFIB nuclear factor I/B
NUP98 nucleoporin 98kDa
PHLDA1 pleckstrin homology-like domain, family A, member 1
POSTN periostin, osteoblast specific factor
PRKCD protein kinase C, delta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SATB1 SATB homeobox 1