BRD-K44227013_ponatinib_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

19 genes differentially expressed following the BRD-K44227013_ponatinib_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
AUTS2 autism susceptibility candidate 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
IFI30 interferon, gamma-inducible protein 30
PHGDH phosphoglycerate dehydrogenase
S100P S100 calcium binding protein P

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CADM1 cell adhesion molecule 1
CCL2 chemokine (C-C motif) ligand 2
CLDN10 claudin 10
DUSP6 dual specificity phosphatase 6
EXOSC4 exosome component 4
GAS1 growth arrest-specific 1
KRT6A keratin 6A, type II
MMP10 matrix metallopeptidase 10
NR4A2 nuclear receptor subfamily 4, group A, member 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase