BRD-K44100512_KIN001-043_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-K44100512_KIN001-043_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AREG amphiregulin
ARHGAP6 Rho GTPase activating protein 6
BAG2 BCL2-associated athanogene 2
COL15A1 collagen, type XV, alpha 1
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DST dystonin
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FZD7 frizzled class receptor 7
GOLGA8A golgin A8 family, member A
HMOX1 heme oxygenase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
LDHB lactate dehydrogenase B
LEF1 lymphoid enhancer-binding factor 1
MAP1B microtubule-associated protein 1B
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMD monocyte to macrophage differentiation-associated
MSX1 msh homeobox 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PHYH phytanoyl-CoA 2-hydroxylase
PPARG peroxisome proliferator-activated receptor gamma
PYGL phosphorylase, glycogen, liver
RAP1GAP RAP1 GTPase activating protein
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SFRP1 secreted frizzled-related protein 1
SPAG4 sperm associated antigen 4
SPON2 spondin 2, extracellular matrix protein
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIM2 tripartite motif containing 2
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALAS1 5'-aminolevulinate synthase 1
ALCAM activated leukocyte cell adhesion molecule
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AMOTL2 angiomotin like 2
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
C14ORF132 chromosome 14 open reading frame 132
CAPN2 calpain 2, (m/II) large subunit
CCND1 cyclin D1
CD200 CD200 molecule
CD9 CD9 molecule
CD93 CD93 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CREB1 cAMP responsive element binding protein 1
DAPK1 death-associated protein kinase 1
DICER1 dicer 1, ribonuclease type III
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESR1 estrogen receptor 1
EXPH5 exophilin 5
FCN1 ficolin (collagen/fibrinogen domain containing) 1
GBP1 guanylate binding protein 1, interferon-inducible
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
H3F3B H3 histone, family 3B (H3.3B)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFITM3 interferon induced transmembrane protein 3
KLK11 kallikrein-related peptidase 11
KRT19 keratin 19, type I
LOXL1 lysyl oxidase-like 1
LXN latexin
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
PAPD7 PAP associated domain containing 7
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PNMA2 paraneoplastic Ma antigen 2
PRUNE2 prune homolog 2 (Drosophila)
PSIP1 PC4 and SFRS1 interacting protein 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRE protein tyrosine phosphatase, receptor type, E
PXDN peroxidasin
RAB31 RAB31, member RAS oncogene family
SCUBE2 signal peptide, CUB domain, EGF-like 2
SELENBP1 selenium binding protein 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPDEF SAM pointed domain containing ETS transcription factor
SPP1 secreted phosphoprotein 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TFF3 trefoil factor 3 (intestinal)
TGFB3 transforming growth factor, beta 3
TNNT1 troponin T type 1 (skeletal, slow)
UGDH UDP-glucose 6-dehydrogenase