BRD-K44100512_KIN001-043_HME1_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

109 genes differentially expressed following the BRD-K44100512_KIN001-043_HME1_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCK3 aarF domain containing kinase 3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
CBS cystathionine-beta-synthase
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CXCR4 chemokine (C-X-C motif) receptor 4
EGR1 early growth response 1
EMX2 empty spiracles homeobox 2
EPCAM epithelial cell adhesion molecule
F5 coagulation factor V (proaccelerin, labile factor)
FUCA1 fucosidase, alpha-L- 1, tissue
G0S2 G0/G1 switch 2
GDF15 growth differentiation factor 15
HCAR3 hydroxycarboxylic acid receptor 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IL1B interleukin 1, beta
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MECOM MDS1 and EVI1 complex locus
MMP7 matrix metallopeptidase 7
NME5 NME/NM23 family member 5
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PLAUR plasminogen activator, urokinase receptor
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8
WIF1 WNT inhibitory factor 1
XBP1 X-box binding protein 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
BAG3 BCL2-associated athanogene 3
BASP1 brain abundant, membrane attached signal protein 1
BEX1 brain expressed, X-linked 1
CALML5 calmodulin-like 5
CBR3 carbonyl reductase 3
CCNF cyclin F
CFD complement factor D (adipsin)
CHIC2 cysteine-rich hydrophobic domain 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
DSC2 desmocollin 2
DST dystonin
DUSP1 dual specificity phosphatase 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FGFBP1 fibroblast growth factor binding protein 1
GAS1 growth arrest-specific 1
GATA3 GATA binding protein 3
GJA1 gap junction protein, alpha 1, 43kDa
GPRC5A G protein-coupled receptor, class C, group 5, member A
H2AFX H2A histone family, member X
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
HSPA1A heat shock 70kDa protein 1A
KDM3A lysine (K)-specific demethylase 3A
KLHL9 kelch-like family member 9
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT14 keratin 14, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KYNU kynureninase
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MAP7 microtubule-associated protein 7
MATN2 matrilin 2
MFSD10 major facilitator superfamily domain containing 10
NFIB nuclear factor I/B
NID1 nidogen 1
PBX3 pre-B-cell leukemia homeobox 3
PDGFA platelet-derived growth factor alpha polypeptide
PEG10 paternally expressed 10
PPL periplakin
RNH1 ribonuclease/angiogenin inhibitor 1
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S100A10 S100 calcium binding protein A10
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SFN stratifin
SOX11 SRY (sex determining region Y)-box 11
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SRPX sushi-repeat containing protein, X-linked
SWAP70 SWAP switching B-cell complex 70kDa subunit
TACC2 transforming, acidic coiled-coil containing protein 2
TCF4 transcription factor 4
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF1 transmembrane 4 L six family member 1
TP63 tumor protein p63
TRIM29 tripartite motif containing 29
TUBA1A tubulin, alpha 1a
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
UGDH UDP-glucose 6-dehydrogenase
WWTR1 WW domain containing transcription regulator 1
ZFP36L2 ZFP36 ring finger protein-like 2