BRD-K43744935_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K43744935_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG2 BTG family, member 2
CCNG2 cyclin G2
CD24 CD24 molecule
CDK19 cyclin-dependent kinase 19
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRIP2 cysteine-rich protein 2
DDIT4 DNA-damage-inducible transcript 4
ERBB2 erb-b2 receptor tyrosine kinase 2
GBP2 guanylate binding protein 2, interferon-inducible
GRN granulin
GSTA1 glutathione S-transferase alpha 1
HEBP1 heme binding protein 1
HIST1H2BG histone cluster 1, H2bg
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
LXN latexin
MYO6 myosin VI
PHYH phytanoyl-CoA 2-hydroxylase
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRUNE2 prune homolog 2 (Drosophila)
PYCARD PYD and CARD domain containing
RAB13 RAB13, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RBKS ribokinase
S100A12 S100 calcium binding protein A12
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC38A1 solute carrier family 38, member 1
STAP2 signal transducing adaptor family member 2
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
CHEK1 checkpoint kinase 1
CKLF chemokine-like factor
CTSC cathepsin C
CXCL12 chemokine (C-X-C motif) ligand 12
DKK1 dickkopf WNT signaling pathway inhibitor 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GREB1 growth regulation by estrogen in breast cancer 1
IFI44 interferon-induced protein 44
IL17RB interleukin 17 receptor B
KIF14 kinesin family member 14
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
NOLC1 nucleolar and coiled-body phosphoprotein 1
NRIP1 nuclear receptor interacting protein 1
ODC1 ornithine decarboxylase 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK1 polo-like kinase 1
PRSS23 protease, serine, 23
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
TRIP13 thyroid hormone receptor interactor 13
ZWILCH zwilch kinetochore protein