BRD-K43389698_BMS-387032_MCF7_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K43389698_BMS-387032_MCF7_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AQP9 aquaporin 9
BHLHE41 basic helix-loop-helix family, member e41
CCL20 chemokine (C-C motif) ligand 20
CFH complement factor H
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CSTA cystatin A (stefin A)
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAXX death-domain associated protein
DCN decorin
DEFB1 defensin, beta 1
DLK1 delta-like 1 homolog (Drosophila)
EIF5A eukaryotic translation initiation factor 5A
FBN1 fibrillin 1
FGFR3 fibroblast growth factor receptor 3
FLRT2 fibronectin leucine rich transmembrane protein 2
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IARS isoleucyl-tRNA synthetase
IL1R2 interleukin 1 receptor, type II
IL1RN interleukin 1 receptor antagonist
IQCG IQ motif containing G
ITM2A integral membrane protein 2A
LAPTM4B lysosomal protein transmembrane 4 beta
MAOB monoamine oxidase B
MMP7 matrix metallopeptidase 7
NTS neurotensin
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PEG3 paternally expressed 3
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCZ protein kinase C, zeta
PSAT1 phosphoserine aminotransferase 1
RBP1 retinol binding protein 1, cellular
RGS2 regulator of G-protein signaling 2
SATB1 SATB homeobox 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SORD sorbitol dehydrogenase
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPG20 spastic paraplegia 20 (Troyer syndrome)
STAR steroidogenic acute regulatory protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRIB2 tribbles pseudokinase 2
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADM adrenomedullin
AMIGO2 adhesion molecule with Ig-like domain 2
AUTS2 autism susceptibility candidate 2
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CADM1 cell adhesion molecule 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD200 CD200 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CXCL9 chemokine (C-X-C motif) ligand 9
DENND1B DENN/MADD domain containing 1B
DUSP6 dual specificity phosphatase 6
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXB7 homeobox B7
IER5 immediate early response 5
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
LGALS3 lectin, galactoside-binding, soluble, 3
LMO3 LIM domain only 3 (rhombotin-like 2)
NAV2 neuron navigator 2
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PEG10 paternally expressed 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
RPL31 ribosomal protein L31
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
XIST X inactive specific transcript (non-protein coding)