BRD-K43389698_BMS-387032_HT29_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K43389698_BMS-387032_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1C3 aldo-keto reductase family 1, member C3
ARL4C ADP-ribosylation factor-like 4C
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
CADPS2 Ca++-dependent secretion activator 2
CD52 CD52 molecule
DLX2 distal-less homeobox 2
FKBP14 FK506 binding protein 14, 22 kDa
FOLR1 folate receptor 1 (adult)
FZD5 frizzled class receptor 5
GLIPR1 GLI pathogenesis-related 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
METTL7A methyltransferase like 7A
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NELL2 NEL-like 2 (chicken)
PAWR PRKC, apoptosis, WT1, regulator
PDPN podoplanin
PSPH phosphoserine phosphatase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBP1 retinol binding protein 1, cellular
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SYT1 synaptotagmin I
TCTN1 tectonic family member 1
THBS1 thrombospondin 1
TNNT1 troponin T type 1 (skeletal, slow)
TRAPPC6A trafficking protein particle complex 6A
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AREG amphiregulin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL2 B-cell CLL/lymphoma 2
CCL4 chemokine (C-C motif) ligand 4
CD24 CD24 molecule
CD38 CD38 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFD complement factor D (adipsin)
CHMP4A charged multivesicular body protein 4A
CP ceruloplasmin (ferroxidase)
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM129A family with sequence similarity 129, member A
FGG fibrinogen gamma chain
G0S2 G0/G1 switch 2
GBP1 guanylate binding protein 1, interferon-inducible
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GTPBP8 GTP-binding protein 8 (putative)
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HBB hemoglobin, beta
HOXC10 homeobox C10
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
KIF2C kinesin family member 2C
KIF5B kinesin family member 5B
KRT15 keratin 15, type I
KRT23 keratin 23, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LGMN legumain
MAOB monoamine oxidase B
MGLL monoglyceride lipase
MME membrane metallo-endopeptidase
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYLK myosin light chain kinase
NRIP1 nuclear receptor interacting protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PMP22 peripheral myelin protein 22
POU2AF1 POU class 2 associating factor 1
PYGB phosphorylase, glycogen; brain
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SFRP1 secreted frizzled-related protein 1
TFF1 trefoil factor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNS1 tensin 1
VTCN1 V-set domain containing T cell activation inhibitor 1