BRD-K43389698_BMS-387032_HME1_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

111 genes differentially expressed following the BRD-K43389698_BMS-387032_HME1_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD2 abhydrolase domain containing 2
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
APOD apolipoprotein D
BHLHE40 basic helix-loop-helix family, member e40
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CD163 CD163 molecule
COL1A2 collagen, type I, alpha 2
CXCR4 chemokine (C-X-C motif) receptor 4
DAPK1 death-associated protein kinase 1
EGR1 early growth response 1
EIF5A eukaryotic translation initiation factor 5A
FLRT2 fibronectin leucine rich transmembrane protein 2
GLUL glutamate-ammonia ligase
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI6 interferon, alpha-inducible protein 6
IFITM2 interferon induced transmembrane protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1B interleukin 1, beta
ISG15 ISG15 ubiquitin-like modifier
LAPTM5 lysosomal protein transmembrane 5
LGALS9 lectin, galactoside-binding, soluble, 9
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTBP3 latent transforming growth factor beta binding protein 3
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
MTUS1 microtubule associated tumor suppressor 1
MYO5C myosin VC
NDRG2 NDRG family member 2
NRN1 neuritin 1
NTS neurotensin
PECAM1 platelet/endothelial cell adhesion molecule 1
PIR pirin (iron-binding nuclear protein)
PRAME preferentially expressed antigen in melanoma
PRR7 proline rich 7 (synaptic)
PSPH phosphoserine phosphatase
RBP1 retinol binding protein 1, cellular
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A9 S100 calcium binding protein A9
SNX10 sorting nexin 10
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP3 STEAP family member 3, metalloreductase
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYT1 synaptotagmin I
TFPI2 tissue factor pathway inhibitor 2
TMEM230 transmembrane protein 230
TPD52 tumor protein D52
VSIG4 V-set and immunoglobulin domain containing 4
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADRB2 adrenoceptor beta 2, surface
AURKA aurora kinase A
AURKB aurora kinase B
CCL5 chemokine (C-C motif) ligand 5
CCNF cyclin F
CCNG2 cyclin G2
CD24 CD24 molecule
CDCA4 cell division cycle associated 4
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CGRRF1 cell growth regulator with ring finger domain 1
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL2 chemokine (C-X-C motif) ligand 2
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EIF5 eukaryotic translation initiation factor 5
EPHA3 EPH receptor A3
FOSL2 FOS-like antigen 2
FZD7 frizzled class receptor 7
GATA3 GATA binding protein 3
GREM1 gremlin 1, DAN family BMP antagonist
HAS2 hyaluronan synthase 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HOXA5 homeobox A5
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
JMJD6 jumonji domain containing 6
KDM3A lysine (K)-specific demethylase 3A
KLHL9 kelch-like family member 9
KRT14 keratin 14, type I
PDGFA platelet-derived growth factor alpha polypeptide
PEG10 paternally expressed 10
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLK2 polo-like kinase 2
RPP38 ribonuclease P/MRP 38kDa subunit
S100A10 S100 calcium binding protein A10
S100A2 S100 calcium binding protein A2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A1 solute carrier family 38, member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SOX4 SRY (sex determining region Y)-box 4
STK17A serine/threonine kinase 17a
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TARP TCR gamma alternate reading frame protein
TGFBR3 transforming growth factor, beta receptor III
TLR4 toll-like receptor 4
TNPO1 transportin 1
TSC22D2 TSC22 domain family, member 2
TSC22D3 TSC22 domain family, member 3
UGDH UDP-glucose 6-dehydrogenase
XBP1 X-box binding protein 1
ZFP36L2 ZFP36 ring finger protein-like 2