BRD-K43389675_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

210 genes differentially expressed following the BRD-K43389675_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ADGRF5 adhesion G protein-coupled receptor F5
AEBP1 AE binding protein 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPN asporin
BEX4 brain expressed, X-linked 4
BLNK B-cell linker
C3ORF14 chromosome 3 open reading frame 14
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CD47 CD47 molecule
CD99 CD99 molecule
CETN2 centrin, EF-hand protein, 2
CFB complement factor B
COG5 component of oligomeric golgi complex 5
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CYBRD1 cytochrome b reductase 1
DCN decorin
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
EGFL6 EGF-like-domain, multiple 6
EIF5A eukaryotic translation initiation factor 5A
ESRP1 epithelial splicing regulatory protein 1
GAS6 growth arrest-specific 6
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
GPNMB glycoprotein (transmembrane) nmb
GULP1 GULP, engulfment adaptor PTB domain containing 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGFBP7 insulin-like growth factor binding protein 7
ISYNA1 inositol-3-phosphate synthase 1
ITM2A integral membrane protein 2A
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
L1CAM L1 cell adhesion molecule
LUM lumican
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAOA monoamine oxidase A
METRN meteorin, glial cell differentiation regulator
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
NMU neuromedin U
NREP neuronal regeneration related protein
OARD1 O-acyl-ADP-ribose deacylase 1
PBX3 pre-B-cell leukemia homeobox 3
PEG3 paternally expressed 3
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSPH phosphoserine phosphatase
PTPRC protein tyrosine phosphatase, receptor type, C
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SELENBP1 selenium binding protein 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFTPB surfactant protein B
SH3BGR SH3 domain binding glutamate-rich protein
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STS steroid sulfatase (microsomal), isozyme S
TCF21 transcription factor 21
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMSB15A thymosin beta 15a
TNNT1 troponin T type 1 (skeletal, slow)
TPGS2 tubulin polyglutamylase complex subunit 2
TSPAN4 tetraspanin 4
TSPAN7 tetraspanin 7
TUBA1A tubulin, alpha 1a
TUSC3 tumor suppressor candidate 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGP2 UDP-glucose pyrophosphorylase 2
VIM vimentin
WFDC1 WAP four-disulfide core domain 1
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACTN1 actinin, alpha 1
ADM adrenomedullin
ADNP activity-dependent neuroprotector homeobox
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADORA2B adenosine A2b receptor
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
BAG3 BCL2-associated athanogene 3
BAG5 BCL2-associated athanogene 5
BLCAP bladder cancer associated protein
BMP4 bone morphogenetic protein 4
BRD4 bromodomain containing 4
CCNA2 cyclin A2
CDC25B cell division cycle 25B
CDCA4 cell division cycle associated 4
CDK7 cyclin-dependent kinase 7
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHERP calcium homeostasis endoplasmic reticulum protein
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
CTSH cathepsin H
CXCL14 chemokine (C-X-C motif) ligand 14
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP14 dual specificity phosphatase 14
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EED embryonic ectoderm development
EGFR epidermal growth factor receptor
EGR2 early growth response 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPS8 epidermal growth factor receptor pathway substrate 8
EXOSC4 exosome component 4
FASTKD5 FAST kinase domains 5
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
FZD7 frizzled class receptor 7
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATA2 GATA binding protein 2
GOSR1 golgi SNAP receptor complex member 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRWD1 glutamate-rich WD repeat containing 1
HNMT histamine N-methyltransferase
HOMER1 homer scaffolding protein 1
HOXA10 homeobox A10
HSPA2 heat shock 70kDa protein 2
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IER2 immediate early response 2
IER3 immediate early response 3
IGFBP4 insulin-like growth factor binding protein 4
INPP1 inositol polyphosphate-1-phosphatase
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
JMJD6 jumonji domain containing 6
KAT6A K(lysine) acetyltransferase 6A
KCTD12 potassium channel tetramerization domain containing 12
KIAA0907 KIAA0907
KIF23 kinesin family member 23
KIF2A kinesin heavy chain member 2A
KIZ kizuna centrosomal protein
KLF4 Kruppel-like factor 4 (gut)
LDLR low density lipoprotein receptor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK6 mitogen-activated protein kinase 6
MARCKS myristoylated alanine-rich protein kinase C substrate
MAT2A methionine adenosyltransferase II, alpha
MCL1 myeloid cell leukemia 1
MMP7 matrix metallopeptidase 7
MSL1 male-specific lethal 1 homolog (Drosophila)
MTCL1 microtubule crosslinking factor 1
MTF2 metal response element binding transcription factor 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NET1 neuroepithelial cell transforming 1
NOP16 NOP16 nucleolar protein
NOP56 NOP56 ribonucleoprotein
NOSIP nitric oxide synthase interacting protein
NUP62 nucleoporin 62kDa
NXT1 nuclear transport factor 2-like export factor 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLK1 polo-like kinase 1
POU2AF1 POU class 2 associating factor 1
PPARG peroxisome proliferator-activated receptor gamma
PPIF peptidylprolyl isomerase F
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKD2 protein kinase D2
PUM1 pumilio RNA-binding family member 1
RAB5C RAB5C, member RAS oncogene family
RGS2 regulator of G-protein signaling 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SF3B4 splicing factor 3b, subunit 4, 49kDa
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMAD3 SMAD family member 3
SNRPE small nuclear ribonucleoprotein polypeptide E
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNJ2 synaptojanin 2
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TBP TATA box binding protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNPO1 transportin 1
TSC22D2 TSC22 domain family, member 2
TXLNA taxilin alpha
USP22 ubiquitin specific peptidase 22
WDR43 WD repeat domain 43
WEE1 WEE1 G2 checkpoint kinase
WIPF2 WAS/WASL interacting protein family, member 2
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZMIZ1 zinc finger, MIZ-type containing 1