BRD-K43330982_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K43330982_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
APOL6 apolipoprotein L, 6
ASNS asparagine synthetase (glutamine-hydrolyzing)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CSTA cystatin A (stefin A)
CTSZ cathepsin Z
DDIT4 DNA-damage-inducible transcript 4
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
GDF15 growth differentiation factor 15
KANK1 KN motif and ankyrin repeat domains 1
LY75 lymphocyte antigen 75
MAP7 microtubule-associated protein 7
MLPH melanophilin
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PSAT1 phosphoserine aminotransferase 1
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A8 S100 calcium binding protein A8
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TBC1D16 TBC1 domain family, member 16
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CSRP2 cysteine and glycine-rich protein 2
EFNB2 ephrin-B2
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GLIPR1 GLI pathogenesis-related 1
HSPB8 heat shock 22kDa protein 8
LGALS3 lectin, galactoside-binding, soluble, 3
LPAR6 lysophosphatidic acid receptor 6
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MSLN mesothelin
PEG10 paternally expressed 10
RGS1 regulator of G-protein signaling 1
RGS5 regulator of G-protein signaling 5
SLPI secretory leukocyte peptidase inhibitor
STAB1 stabilin 1
TFPI2 tissue factor pathway inhibitor 2
VAMP8 vesicle-associated membrane protein 8