BRD-K43068349_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K43068349_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
BTG2 BTG family, member 2
CAV2 caveolin 2
CCL4 chemokine (C-C motif) ligand 4
CD200 CD200 molecule
CLC Charcot-Leyden crystal galectin
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KIAA0226L KIAA0226-like
MAN1A1 mannosidase, alpha, class 1A, member 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MXRA5 matrix-remodelling associated 5
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PCLO piccolo presynaptic cytomatrix protein
PDE4B phosphodiesterase 4B, cAMP-specific
PLAT plasminogen activator, tissue
RGS5 regulator of G-protein signaling 5
S100P S100 calcium binding protein P
STX1A syntaxin 1A (brain)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ANGPT1 angiopoietin 1
DIO1 deiodinase, iodothyronine, type I
FOLR1 folate receptor 1 (adult)
FPGS folylpolyglutamate synthase
KLF6 Kruppel-like factor 6
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
PDGFC platelet derived growth factor C
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPP1 selenoprotein P, plasma, 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
VCAN versican