BRD-K43068349_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K43068349_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CD200 CD200 molecule
CD24 CD24 molecule
CLDN3 claudin 3
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
F2RL1 coagulation factor II (thrombin) receptor-like 1
FXYD5 FXYD domain containing ion transport regulator 5
H1F0 H1 histone family, member 0
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PHGDH phosphoglycerate dehydrogenase
PROM1 prominin 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ANOS1 anosmin 1
AOX1 aldehyde oxidase 1
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CDK6 cyclin-dependent kinase 6
DLD dihydrolipoamide dehydrogenase
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAM107A family with sequence similarity 107, member A
FLRT2 fibronectin leucine rich transmembrane protein 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA8 heat shock 70kDa protein 8
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
NFIB nuclear factor I/B
ODC1 ornithine decarboxylase 1
PDGFC platelet derived growth factor C
POSTN periostin, osteoblast specific factor
PTGER4 prostaglandin E receptor 4 (subtype EP4)
TNC tenascin C