BRD-K43002773_GDC-0068_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K43002773_GDC-0068_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
AGR2 anterior gradient 2
AXIN1 axin 1
CADM1 cell adhesion molecule 1
CLGN calmegin
COCH cochlin
CRISP3 cysteine-rich secretory protein 3
CRYL1 crystallin, lambda 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB3 erb-b2 receptor tyrosine kinase 3
FOXO4 forkhead box O4
GPR137B G protein-coupled receptor 137B
GSTM3 glutathione S-transferase mu 3 (brain)
HLA-DRA major histocompatibility complex, class II, DR alpha
HNMT histamine N-methyltransferase
IGFBP7 insulin-like growth factor binding protein 7
IL1R1 interleukin 1 receptor, type I
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MMP7 matrix metallopeptidase 7
MYC v-myc avian myelocytomatosis viral oncogene homolog
NRIP1 nuclear receptor interacting protein 1
NSG1 neuron specific gene family member 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PRKCA protein kinase C, alpha
RBM47 RNA binding motif protein 47
RIN2 Ras and Rab interactor 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SMAD3 SMAD family member 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SYNJ2 synaptojanin 2
THBS1 thrombospondin 1
TSPAN12 tetraspanin 12
TSPAN4 tetraspanin 4
VCAM1 vascular cell adhesion molecule 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CRELD2 cysteine-rich with EGF-like domains 2
CSTA cystatin A (stefin A)
FABP7 fatty acid binding protein 7, brain
FBLN1 fibulin 1
FHL1 four and a half LIM domains 1
FOXJ3 forkhead box J3
G0S2 G0/G1 switch 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
LMO4 LIM domain only 4
MECOM MDS1 and EVI1 complex locus
MMP1 matrix metallopeptidase 1
NRN1 neuritin 1
PDIA3 protein disulfide isomerase family A, member 3
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STK17A serine/threonine kinase 17a
TAGLN2 transgelin 2
VDAC1 voltage-dependent anion channel 1
WDR7 WD repeat domain 7
ZNF395 zinc finger protein 395