BRD-K42918627_GSK-2126458_HME1_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

95 genes differentially expressed following the BRD-K42918627_GSK-2126458_HME1_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABHD4 abhydrolase domain containing 4
ACACB acetyl-CoA carboxylase beta
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4A ADP-ribosylation factor-like 4A
ATF3 activating transcription factor 3
BTG1 B-cell translocation gene 1, anti-proliferative
C8ORF4 chromosome 8 open reading frame 4
CBR3 carbonyl reductase 3
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLCA1 chloride channel accessory 1
CLEC2B C-type lectin domain family 2, member B
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRYAB crystallin, alpha B
CTH cystathionine gamma-lyase
DCN decorin
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
F8 coagulation factor VIII, procoagulant component
FAM13A family with sequence similarity 13, member A
FBN1 fibrillin 1
FZD7 frizzled class receptor 7
HBB hemoglobin, beta
HOXC6 homeobox C6
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGFBP5 insulin-like growth factor binding protein 5
IL6ST interleukin 6 signal transducer
IRS2 insulin receptor substrate 2
KLF9 Kruppel-like factor 9
KLHL21 kelch-like family member 21
LRRC16A leucine rich repeat containing 16A
METTL7A methyltransferase like 7A
NFIB nuclear factor I/B
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUPR1 nuclear protein, transcriptional regulator, 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLS3 plastin 3
POSTN periostin, osteoblast specific factor
PSD3 pleckstrin and Sec7 domain containing 3
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RGS2 regulator of G-protein signaling 2
RNF24 ring finger protein 24
RSRP1 arginine/serine-rich protein 1
SESN1 sestrin 1
SOX4 SRY (sex determining region Y)-box 4
TOX3 TOX high mobility group box family member 3
TRIM22 tripartite motif containing 22
TSC22D3 TSC22 domain family, member 3
ZNF217 zinc finger protein 217

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ADIRF adipogenesis regulatory factor
AQP3 aquaporin 3 (Gill blood group)
CAV2 caveolin 2
CCDC86 coiled-coil domain containing 86
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CES1 carboxylesterase 1
CSTA cystatin A (stefin A)
CTPS1 CTP synthase 1
CYB5A cytochrome b5 type A (microsomal)
DENND1B DENN/MADD domain containing 1B
DUSP14 dual specificity phosphatase 14
ENO1 enolase 1, (alpha)
G0S2 G0/G1 switch 2
IL1B interleukin 1, beta
JMJD6 jumonji domain containing 6
KLHL9 kelch-like family member 9
KRT5 keratin 5, type II
MAT2A methionine adenosyltransferase II, alpha
MSMO1 methylsterol monooxygenase 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NOP16 NOP16 nucleolar protein
PEA15 phosphoprotein enriched in astrocytes 15
PI3 peptidase inhibitor 3, skin-derived
PSCA prostate stem cell antigen
PTGDS prostaglandin D2 synthase 21kDa (brain)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SDC4 syndecan 4
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLPI secretory leukocyte peptidase inhibitor
SNAP25 synaptosomal-associated protein, 25kDa
SOX9 SRY (sex determining region Y)-box 9
SPRR3 small proline-rich protein 3
STIP1 stress-induced phosphoprotein 1
TACSTD2 tumor-associated calcium signal transducer 2
TES testin LIM domain protein