BRD-K42918627_GSK-2126458_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

83 genes differentially expressed following the BRD-K42918627_GSK-2126458_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
ARID5B AT rich interactive domain 5B (MRF1-like)
BCL6 B-cell CLL/lymphoma 6
C1S complement component 1, s subcomponent
CA12 carbonic anhydrase XII
CCNG2 cyclin G2
CDK14 cyclin-dependent kinase 14
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
EAPP E2F-associated phosphoprotein
FRS2 fibroblast growth factor receptor substrate 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IGFBP5 insulin-like growth factor binding protein 5
KLF9 Kruppel-like factor 9
LOX lysyl oxidase
LPL lipoprotein lipase
LTBP1 latent transforming growth factor beta binding protein 1
MYBPC1 myosin binding protein C, slow type
NAMPT nicotinamide phosphoribosyltransferase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PTN pleiotrophin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RB1CC1 RB1-inducible coiled-coil 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SNX7 sorting nexin 7
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
SPARCL1 SPARC-like 1 (hevin)
SYBU syntabulin (syntaxin-interacting)
TAGLN transgelin
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TGFBI transforming growth factor, beta-induced, 68kDa
THBS4 thrombospondin 4
TSC22D3 TSC22 domain family, member 3
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLIC5 chloride intracellular channel 5
DACH1 dachshund family transcription factor 1
DCLK1 doublecortin-like kinase 1
DUSP14 dual specificity phosphatase 14
EIF4A1 eukaryotic translation initiation factor 4A1
EPHA3 EPH receptor A3
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOSL1 FOS-like antigen 1
FRZB frizzled-related protein
GNAS GNAS complex locus
GOLGA8B golgin A8 family, member B
GOLGA8H golgin A8 family, member H
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBEGF heparin-binding EGF-like growth factor
HOXA10 homeobox A10
HSPA1A heat shock 70kDa protein 1A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LIMCH1 LIM and calponin homology domains 1
LMO3 LIM domain only 3 (rhombotin-like 2)
MAT2A methionine adenosyltransferase II, alpha
MKNK1 MAP kinase interacting serine/threonine kinase 1
NFASC neurofascin
PHLDA2 pleckstrin homology-like domain, family A, member 2
PMP22 peripheral myelin protein 22
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A6 S100 calcium binding protein A6
S100A8 S100 calcium binding protein A8
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMAD7 SMAD family member 7
SOX11 SRY (sex determining region Y)-box 11
SRSF7 serine/arginine-rich splicing factor 7
TM4SF1 transmembrane 4 L six family member 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TUBB3 tubulin, beta 3 class III
TUBB6 tubulin, beta 6 class V
VIM vimentin
ZEB2 zinc finger E-box binding homeobox 2
ZFP36 ZFP36 ring finger protein