BRD-K42805893_HG-14-8-02_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

109 genes differentially expressed following the BRD-K42805893_HG-14-8-02_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL2 angiomotin like 2
ATP9A ATPase, class II, type 9A
BPIFA1 BPI fold containing family A, member 1
C3 complement component 3
CASP7 caspase 7, apoptosis-related cysteine peptidase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLU clusterin
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COBLL1 cordon-bleu WH2 repeat protein-like 1
CPD carboxypeptidase D
CSTA cystatin A (stefin A)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GNAS GNAS complex locus
GSTA1 glutathione S-transferase alpha 1
HIST1H2AC histone cluster 1, H2ac
HOXC6 homeobox C6
IFI27 interferon, alpha-inducible protein 27
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
LRRC16A leucine rich repeat containing 16A
MME membrane metallo-endopeptidase
MSMB microseminoprotein, beta-
MUC1 mucin 1, cell surface associated
MVP major vault protein
MYLK myosin light chain kinase
MYO6 myosin VI
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUPR1 nuclear protein, transcriptional regulator, 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PPL periplakin
PRSS23 protease, serine, 23
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
SLC38A1 solute carrier family 38, member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TACSTD2 tumor-associated calcium signal transducer 2
TOX3 TOX high mobility group box family member 3
TSPAN12 tetraspanin 12
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase
VGLL3 vestigial-like family member 3
WFDC2 WAP four-disulfide core domain 2
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CALML5 calmodulin-like 5
CHIC2 cysteine-rich hydrophobic domain 2
CLC Charcot-Leyden crystal galectin
COL6A2 collagen, type VI, alpha 2
COTL1 coactosin-like F-actin binding protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
ETV1 ets variant 1
ETV5 ets variant 5
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FOSL1 FOS-like antigen 1
FST follistatin
HBEGF heparin-binding EGF-like growth factor
IER3 immediate early response 3
IER5 immediate early response 5
IFRD2 interferon-related developmental regulator 2
KLK5 kallikrein-related peptidase 5
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALL mal, T-cell differentiation protein-like
MT1E metallothionein 1E
NAMPT nicotinamide phosphoribosyltransferase
NPTX2 neuronal pentraxin II
NT5E 5'-nucleotidase, ecto (CD73)
PDE4B phosphodiesterase 4B, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRSS3 protease, serine, 3
PTX3 pentraxin 3, long
RAB20 RAB20, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBP1 retinol binding protein 1, cellular
RFC2 replication factor C (activator 1) 2, 40kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RGS2 regulator of G-protein signaling 2
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RPS4Y1 ribosomal protein S4, Y-linked 1
RRM2 ribonucleotide reductase M2
SFRP1 secreted frizzled-related protein 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
STC1 stanniocalcin 1
STX1A syntaxin 1A (brain)
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TSPAN4 tetraspanin 4