BRD-K42728290_NVP-BGJ398_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-K42728290_NVP-BGJ398_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM10 ADAM metallopeptidase domain 10
ADCY1 adenylate cyclase 1 (brain)
CCDC92 coiled-coil domain containing 92
CDC42 cell division cycle 42
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CP ceruloplasmin (ferroxidase)
CREB1 cAMP responsive element binding protein 1
DEGS1 delta(4)-desaturase, sphingolipid 1
E2F2 E2F transcription factor 2
EPAS1 endothelial PAS domain protein 1
GBP2 guanylate binding protein 2, interferon-inducible
GDF15 growth differentiation factor 15
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPNMB glycoprotein (transmembrane) nmb
GPX3 glutathione peroxidase 3
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KLHL21 kelch-like family member 21
KYNU kynureninase
MAOA monoamine oxidase A
NID2 nidogen 2 (osteonidogen)
PEX11A peroxisomal biogenesis factor 11 alpha
PLIN2 perilipin 2
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SLC38A1 solute carrier family 38, member 1
SOD2 superoxide dismutase 2, mitochondrial
SPAG4 sperm associated antigen 4
TRA2A transformer 2 alpha homolog (Drosophila)
USP3 ubiquitin specific peptidase 3

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
ATF1 activating transcription factor 1
CNN3 calponin 3, acidic
COPS7A COP9 signalosome subunit 7A
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ESR1 estrogen receptor 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INHBB inhibin, beta B
METRN meteorin, glial cell differentiation regulator
MYCBP MYC binding protein
NME1 NME/NM23 nucleoside diphosphate kinase 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSPH phosphoserine phosphatase
QDPR quinoid dihydropteridine reductase
RPS11 ribosomal protein S11