BRD-K42728290_NVP-BGJ398_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K42728290_NVP-BGJ398_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
ATF3 activating transcription factor 3
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CFLAR CASP8 and FADD-like apoptosis regulator
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EFNB2 ephrin-B2
EMX2 empty spiracles homeobox 2
HIST1H1C histone cluster 1, H1c
HTRA1 HtrA serine peptidase 1
KRT18 keratin 18, type I
LOX lysyl oxidase
MEIS1 Meis homeobox 1
NFE2L2 nuclear factor, erythroid 2-like 2
NGRN neugrin, neurite outgrowth associated
NOX4 NADPH oxidase 4
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
P3H2 prolyl 3-hydroxylase 2
PEG10 paternally expressed 10
PRC1 protein regulator of cytokinesis 1
RTN2 reticulon 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SOD2 superoxide dismutase 2, mitochondrial
SPON1 spondin 1, extracellular matrix protein
SULF1 sulfatase 1
TFRC transferrin receptor
TPD52L1 tumor protein D52-like 1
UGCG UDP-glucose ceramide glucosyltransferase
VLDLR very low density lipoprotein receptor
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ADIRF adipogenesis regulatory factor
BPHL biphenyl hydrolase-like (serine hydrolase)
C6ORF62 chromosome 6 open reading frame 62
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL12 chemokine (C-X-C motif) ligand 12
DCLK1 doublecortin-like kinase 1
FERMT1 fermitin family member 1
FHL1 four and a half LIM domains 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IFI6 interferon, alpha-inducible protein 6
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGL immunoglobulin lambda locus
IL6R interleukin 6 receptor
MEF2C myocyte enhancer factor 2C
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NQO2 NAD(P)H dehydrogenase, quinone 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PAH phenylalanine hydroxylase
RPS11 ribosomal protein S11
SRPX sushi-repeat containing protein, X-linked
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNS3 tensin 3
VDAC1 voltage-dependent anion channel 1
ZMYM2 zinc finger, MYM-type 2
ZNF589 zinc finger protein 589