BRD-K42693031_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K42693031_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ATP10D ATPase, class V, type 10D
BID BH3 interacting domain death agonist
CCNA1 cyclin A1
CNPY3 canopy FGF signaling regulator 3
COMMD8 COMM domain containing 8
EMX2 empty spiracles homeobox 2
EXT1 exostosin glycosyltransferase 1
HIST1H1C histone cluster 1, H1c
IFITM1 interferon induced transmembrane protein 1
ISG15 ISG15 ubiquitin-like modifier
JCHAIN joining chain of multimeric IgA and IgM
LOC100505650 uncharacterized LOC100505650
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
TPM2 tropomyosin 2 (beta)
ZNF124 zinc finger protein 124

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
AK1 adenylate kinase 1
C3 complement component 3
CCDC86 coiled-coil domain containing 86
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FGG fibrinogen gamma chain
GAL galanin/GMAP prepropeptide
IGFBP4 insulin-like growth factor binding protein 4
IRS2 insulin receptor substrate 2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
NFIB nuclear factor I/B
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLTP phospholipid transfer protein
POSTN periostin, osteoblast specific factor
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SORD sorbitol dehydrogenase