BRD-K42687792_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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91 genes differentially expressed following the BRD-K42687792_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN4 actinin, alpha 4
AHCYL1 adenosylhomocysteinase-like 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C4BPA complement component 4 binding protein, alpha
CA12 carbonic anhydrase XII
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL18A1 collagen, type XVIII, alpha 1
COL4A2 collagen, type IV, alpha 2
COL4A5 collagen, type IV, alpha 5
COL6A1 collagen, type VI, alpha 1
DDR1 discoidin domain receptor tyrosine kinase 1
ENO2 enolase 2 (gamma, neuronal)
EVL Enah/Vasp-like
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGFR3 fibroblast growth factor receptor 3
G6PD glucose-6-phosphate dehydrogenase
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSTA4 glutathione S-transferase alpha 4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP4 insulin-like growth factor binding protein 4
LDOC1 leucine zipper, down-regulated in cancer 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAP7 microtubule-associated protein 7
MLPH melanophilin
NUCB1 nucleobindin 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PDZK1 PDZ domain containing 1
PDZK1IP1 PDZK1 interacting protein 1
PPL periplakin
PRKCD protein kinase C, delta
RGS2 regulator of G-protein signaling 2
S100A12 S100 calcium binding protein A12
SFTPC surfactant protein C
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TSKU tsukushi, small leucine rich proteoglycan

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADI1 acireductone dioxygenase 1
ANXA1 annexin A1
ANXA3 annexin A3
ANXA7 annexin A7
ARMCX1 armadillo repeat containing, X-linked 1
ATF1 activating transcription factor 1
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
C1ORF54 chromosome 1 open reading frame 54
CCNE2 cyclin E2
CD36 CD36 molecule (thrombospondin receptor)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COL11A1 collagen, type XI, alpha 1
COMMD8 COMM domain containing 8
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL9 chemokine (C-X-C motif) ligand 9
CYCS cytochrome c, somatic
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A eukaryotic translation initiation factor 5A
FNTA farnesyltransferase, CAAX box, alpha
G0S2 G0/G1 switch 2
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GTF3A general transcription factor IIIA
GTPBP8 GTP-binding protein 8 (putative)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HIST1H4C histone cluster 1, H4c
ICAM2 intercellular adhesion molecule 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFRD2 interferon-related developmental regulator 2
IL1R1 interleukin 1 receptor, type I
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
LDHB lactate dehydrogenase B
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LXN latexin
LYPLA1 lysophospholipase I
MAT2B methionine adenosyltransferase II, beta
MFAP5 microfibrillar associated protein 5
MRPL15 mitochondrial ribosomal protein L15
NUTF2 nuclear transport factor 2
OAT ornithine aminotransferase
PAK1IP1 PAK1 interacting protein 1
PRDX3 peroxiredoxin 3
PRNP prion protein
RPS27L ribosomal protein S27-like
SRSF6 serine/arginine-rich splicing factor 6
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TXNDC9 thioredoxin domain containing 9