BRD-K42436189_AZ20_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K42436189_AZ20_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL11A1 collagen, type XI, alpha 1
COMT catechol-O-methyltransferase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DICER1 dicer 1, ribonuclease type III
DLC1 DLC1 Rho GTPase activating protein
DLK1 delta-like 1 homolog (Drosophila)
GAL galanin/GMAP prepropeptide
GDF15 growth differentiation factor 15
H1F0 H1 histone family, member 0
H3F3B H3 histone, family 3B (H3.3B)
HIST1H1C histone cluster 1, H1c
HIST1H2BK histone cluster 1, H2bk
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NMU neuromedin U
PAN2 PAN2 poly(A) specific ribonuclease subunit
PLAGL1 pleiomorphic adenoma gene-like 1
PROM1 prominin 1
RHOBTB3 Rho-related BTB domain containing 3
RPS11 ribosomal protein S11
RPS27L ribosomal protein S27-like
S100A14 S100 calcium binding protein A14
SELL selectin L
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SESN1 sestrin 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMAD1 SMAD family member 1
STK10 serine/threonine kinase 10
TNNT1 troponin T type 1 (skeletal, slow)
UBE3A ubiquitin protein ligase E3A
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
VDAC1 voltage-dependent anion channel 1
WNK1 WNK lysine deficient protein kinase 1

decreased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD24 CD24 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK14 cyclin-dependent kinase 14
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CISD1 CDGSH iron sulfur domain 1
CLU clusterin
DMTF1 cyclin D binding myb-like transcription factor 1
EPHA3 EPH receptor A3
FGFR2 fibroblast growth factor receptor 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GBP2 guanylate binding protein 2, interferon-inducible
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
IL32 interleukin 32
LRP2 low density lipoprotein receptor-related protein 2
LTBP2 latent transforming growth factor beta binding protein 2
LTF lactotransferrin
MMP12 matrix metallopeptidase 12
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEFH neurofilament, heavy polypeptide
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
NVL nuclear VCP-like
PGM1 phosphoglucomutase 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGCC regulator of cell cycle
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VLDLR very low density lipoprotein receptor
WFDC2 WAP four-disulfide core domain 2
XIST X inactive specific transcript (non-protein coding)