BRD-K42021584_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K42021584_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
CD24 CD24 molecule
CDC42 cell division cycle 42
CPA3 carboxypeptidase A3 (mast cell)
CXCL14 chemokine (C-X-C motif) ligand 14
DACH1 dachshund family transcription factor 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FXYD3 FXYD domain containing ion transport regulator 3
HBB hemoglobin, beta
KLF4 Kruppel-like factor 4 (gut)
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
MGLL monoglyceride lipase
MTSS1 metastasis suppressor 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PCSK1 proprotein convertase subtilisin/kexin type 1
PPAP2B phosphatidic acid phosphatase type 2B
S100A14 S100 calcium binding protein A14
S100A2 S100 calcium binding protein A2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
BST2 bone marrow stromal cell antigen 2
EIF5A eukaryotic translation initiation factor 5A
FGFR2 fibroblast growth factor receptor 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
MDK midkine (neurite growth-promoting factor 2)
MEIS2 Meis homeobox 2
RGS1 regulator of G-protein signaling 1