BRD-K41924482_7674034_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K41924482_7674034_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CLDN8 claudin 8
COLEC12 collectin sub-family member 12
DENND1B DENN/MADD domain containing 1B
EPCAM epithelial cell adhesion molecule
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
IRF6 interferon regulatory factor 6
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK5 kallikrein-related peptidase 5
LAMP3 lysosomal-associated membrane protein 3
MMP9 matrix metallopeptidase 9
NR4A3 nuclear receptor subfamily 4, group A, member 3
OLFML2A olfactomedin-like 2A
RAB25 RAB25, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RHOBTB3 Rho-related BTB domain containing 3
S100A8 S100 calcium binding protein A8
SELENBP1 selenium binding protein 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SPARCL1 SPARC-like 1 (hevin)
STON1 stonin 1
TCEA2 transcription elongation factor A (SII), 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TPPP3 tubulin polymerization-promoting protein family member 3
TRD T cell receptor delta locus

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACAT2 acetyl-CoA acetyltransferase 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDOA aldolase A, fructose-bisphosphate
ANXA5 annexin A5
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
CLU clusterin
CRYAB crystallin, alpha B
CSRP1 cysteine and glycine-rich protein 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
G0S2 G0/G1 switch 2
GPX3 glutathione peroxidase 3
GSTM3 glutathione S-transferase mu 3 (brain)
HAMP hepcidin antimicrobial peptide
HPRT1 hypoxanthine phosphoribosyltransferase 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IL6ST interleukin 6 signal transducer
KCTD5 potassium channel tetramerization domain containing 5
MAP1B microtubule-associated protein 1B
MMP7 matrix metallopeptidase 7
MPZL1 myelin protein zero-like 1
MYBPC1 myosin binding protein C, slow type
NFIB nuclear factor I/B
NPY1R neuropeptide Y receptor Y1
OSBPL9 oxysterol binding protein-like 9
PLA2G16 phospholipase A2, group XVI
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB13 RAB13, member RAS oncogene family
RBP4 retinol binding protein 4, plasma
RNASET2 ribonuclease T2
RNF167 ring finger protein 167
SCD stearoyl-CoA desaturase (delta-9-desaturase)
STOM stomatin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP4 TIMP metallopeptidase inhibitor 4
TSC22D3 TSC22 domain family, member 3
YME1L1 YME1-like 1 ATPase