BRD-K41895714_AS-605240_HME1_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K41895714_AS-605240_HME1_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD4 abhydrolase domain containing 4
ASS1 argininosuccinate synthase 1
CBS cystathionine-beta-synthase
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FGFR3 fibroblast growth factor receptor 3
GADD45B growth arrest and DNA-damage-inducible, beta
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IRF4 interferon regulatory factor 4
IRS2 insulin receptor substrate 2
KAZN kazrin, periplakin interacting protein
LTF lactotransferrin
MAGEA3 melanoma antigen family A3
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PCDH9 protocadherin 9
RDX radixin
RHOBTB3 Rho-related BTB domain containing 3
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SLPI secretory leukocyte peptidase inhibitor
TSC22D3 TSC22 domain family, member 3
TUBB6 tubulin, beta 6 class V
VGLL1 vestigial-like family member 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL4C ADP-ribosylation factor-like 4C
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCHE butyrylcholinesterase
CD44 CD44 molecule (Indian blood group)
CHIC2 cysteine-rich hydrophobic domain 2
CST1 cystatin SN
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL9 chemokine (C-X-C motif) ligand 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL3 dihydropyrimidinase-like 3
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
HMGA2 high mobility group AT-hook 2
HNMT histamine N-methyltransferase
IER3 immediate early response 3
IL1B interleukin 1, beta
ITGA6 integrin, alpha 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MLPH melanophilin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDRG1 N-myc downstream regulated 1
PCP4 Purkinje cell protein 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAT plasminogen activator, tissue
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SNAP25 synaptosomal-associated protein, 25kDa
SOX9 SRY (sex determining region Y)-box 9
SPP1 secreted phosphoprotein 1
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
STC1 stanniocalcin 1
STX1A syntaxin 1A (brain)
TM4SF1 transmembrane 4 L six family member 1
TRBC1 T cell receptor beta constant 1
TRIB2 tribbles pseudokinase 2