BRD-K41895714_AS-605240_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-K41895714_AS-605240_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACTG2 actin, gamma 2, smooth muscle, enteric
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGR2 anterior gradient 2
ALDOC aldolase C, fructose-bisphosphate
APOD apolipoprotein D
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
CALB1 calbindin 1, 28kDa
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CXCL5 chemokine (C-X-C motif) ligand 5
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EDNRB endothelin receptor type B
FAM13A family with sequence similarity 13, member A
FMO2 flavin containing monooxygenase 2 (non-functional)
GATA2 GATA binding protein 2
GPX2 glutathione peroxidase 2
GSN gelsolin
HOPX HOP homeobox
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KLHL21 kelch-like family member 21
KLK11 kallikrein-related peptidase 11
KRT14 keratin 14, type I
KRT4 keratin 4, type II
LGALS3 lectin, galactoside-binding, soluble, 3
MAOA monoamine oxidase A
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
NEBL nebulette
PCP4 Purkinje cell protein 4
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PPARG peroxisome proliferator-activated receptor gamma
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB40B RAB40B, member RAS oncogene family
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SNX11 sorting nexin 11
SPARCL1 SPARC-like 1 (hevin)
TFF1 trefoil factor 1
THSD7A thrombospondin, type I, domain containing 7A
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TOX3 TOX high mobility group box family member 3
TP63 tumor protein p63
TSPAN8 tetraspanin 8
TTC39A tetratricopeptide repeat domain 39A
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
APOB apolipoprotein B
CDC20 cell division cycle 20
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLEC11A C-type lectin domain family 11, member A
CXCL12 chemokine (C-X-C motif) ligand 12
DACT1 dishevelled-binding antagonist of beta-catenin 1
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DUSP6 dual specificity phosphatase 6
FKBP14 FK506 binding protein 14, 22 kDa
FOSL1 FOS-like antigen 1
FZD10 frizzled class receptor 10
G0S2 G0/G1 switch 2
GREM1 gremlin 1, DAN family BMP antagonist
HAPLN1 hyaluronan and proteoglycan link protein 1
HBEGF heparin-binding EGF-like growth factor
HP haptoglobin
IL6 interleukin 6
KIF14 kinesin family member 14
KRT23 keratin 23, type I
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NT5E 5'-nucleotidase, ecto (CD73)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
SCG5 secretogranin V
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SMYD2 SET and MYND domain containing 2
SULF1 sulfatase 1
TFRC transferrin receptor
THBS1 thrombospondin 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TSPAN4 tetraspanin 4
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WBP5 WW domain binding protein 5