BRD-K41731458_TRICLOSAN_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K41731458_TRICLOSAN_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP9A ATPase, class II, type 9A
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDIT4 DNA-damage-inducible transcript 4
EDN3 endothelin 3
GDF15 growth differentiation factor 15
GLUL glutamate-ammonia ligase
H1F0 H1 histone family, member 0
HMOX1 heme oxygenase 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
NOTCH2NL notch 2 N-terminal like
NR2F2 nuclear receptor subfamily 2, group F, member 2
NT5DC2 5'-nucleotidase domain containing 2
OLFM4 olfactomedin 4
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PFKM phosphofructokinase, muscle
PHGDH phosphoglycerate dehydrogenase
PYCR1 pyrroline-5-carboxylate reductase 1
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TRIB3 tribbles pseudokinase 3

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
AMIGO2 adhesion molecule with Ig-like domain 2
C14ORF1 chromosome 14 open reading frame 1
C3 complement component 3
CAV2 caveolin 2
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CRIP1 cysteine-rich protein 1 (intestinal)
DAAM1 dishevelled associated activator of morphogenesis 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DPYSL3 dihydropyrimidinase-like 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB14 growth factor receptor-bound protein 14
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ISG15 ISG15 ubiquitin-like modifier
LBH limb bud and heart development
LCK LCK proto-oncogene, Src family tyrosine kinase
LEF1 lymphoid enhancer-binding factor 1
MARCKSL1 MARCKS-like 1
MSMO1 methylsterol monooxygenase 1
MYRF myelin regulatory factor
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
PBX3 pre-B-cell leukemia homeobox 3
PEG3 paternally expressed 3
PLA2G16 phospholipase A2, group XVI
PODXL podocalyxin-like
S100A10 S100 calcium binding protein A10
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
TM4SF1 transmembrane 4 L six family member 1
TMSB15A thymosin beta 15a
UBAP2 ubiquitin associated protein 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)