BRD-K41713976_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K41713976_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRG2 adhesion G protein-coupled receptor G2
BHLHE41 basic helix-loop-helix family, member e41
CCND2 cyclin D2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHMP4A charged multivesicular body protein 4A
CLIC4 chloride intracellular channel 4
CPE carboxypeptidase E
GUSBP3 glucuronidase, beta pseudogene 3
HBD hemoglobin, delta
IFI6 interferon, alpha-inducible protein 6
IGHM immunoglobulin heavy constant mu
KRT7 keratin 7, type II
LMO3 LIM domain only 3 (rhombotin-like 2)
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LUM lumican
MAP7 microtubule-associated protein 7
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MMP9 matrix metallopeptidase 9
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PLXNC1 plexin C1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
QPCT glutaminyl-peptide cyclotransferase
SLC16A6 solute carrier family 16, member 6
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TBX3 T-box 3
TPD52 tumor protein D52
TUBB2B tubulin, beta 2B class IIb
ZNF131 zinc finger protein 131
ZNF586 zinc finger protein 586
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CAV2 caveolin 2
CERS6 ceramide synthase 6
CES1 carboxylesterase 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FMO2 flavin containing monooxygenase 2 (non-functional)
FOLR1 folate receptor 1 (adult)
FZD7 frizzled class receptor 7
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL32 interleukin 32
NCK1 NCK adaptor protein 1
NEFL neurofilament, light polypeptide
NQO1 NAD(P)H dehydrogenase, quinone 1
P3H2 prolyl 3-hydroxylase 2
PDGFA platelet-derived growth factor alpha polypeptide
PTGER3 prostaglandin E receptor 3 (subtype EP3)
SULF1 sulfatase 1
TNNT1 troponin T type 1 (skeletal, slow)
VTCN1 V-set domain containing T cell activation inhibitor 1