BRD-K41303952_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K41303952_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
AZU1 azurocidin 1
BSG basigin (Ok blood group)
CDA cytidine deaminase
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CECR1 cat eye syndrome chromosome region, candidate 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLC Charcot-Leyden crystal galectin
CPD carboxypeptidase D
CST7 cystatin F (leukocystatin)
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
ELANE elastase, neutrophil expressed
FADS1 fatty acid desaturase 1
FASN fatty acid synthase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
KRT19 keratin 19, type I
LDLR low density lipoprotein receptor
LITAF lipopolysaccharide-induced TNF factor
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MPO myeloperoxidase
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MSMO1 methylsterol monooxygenase 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PRTN3 proteinase 3
RAB11FIP1 RAB11 family interacting protein 1 (class I)
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOX4 SRY (sex determining region Y)-box 4
SQLE squalene epoxidase

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
C1ORF116 chromosome 1 open reading frame 116
CXCL14 chemokine (C-X-C motif) ligand 14
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAPK1 death-associated protein kinase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DPYSL3 dihydropyrimidinase-like 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FCGBP Fc fragment of IgG binding protein
FGFR3 fibroblast growth factor receptor 3
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HOPX HOP homeobox
ICAM2 intercellular adhesion molecule 2
IL13RA2 interleukin 13 receptor, alpha 2
NFIB nuclear factor I/B
RGS4 regulator of G-protein signaling 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRPX sushi-repeat containing protein, X-linked
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TAGLN transgelin